CO-16 means the claim is missing or contains incorrect information that prevents the payer from adjudicating it. Unlike most denials, CO-16 is almost always fixable — the payer isn't saying the service isn't covered, they're saying they can't process what you sent.
80–95% — CO-16 is the most correctable denial in DME billing. The rare failures are CMN issues where the physician is unresponsive or missing documentation that can't be reconstructed.
Get a tailored CO-16 action plan in 30 seconds.
Run CO-16 through Analyzer →30-page DME Denial Code Handbook with paste-ready appeal letters.
Download the Handbook →Usually just a corrected claim resubmission. CO-16 is a "fix and resend" denial, not a medical necessity dispute. No appeal letter needed in most cases.
N264 (CMN not received) and N265 (CMN incomplete) are the most common in HCPCS-based DME billing. The KX modifier omission is the single most frequent cause.
As fast as possible. CO-16 counts against your timely filing window — the payer's clock doesn't stop because of the denial. Most commercial payers give you 30–60 days to resubmit a corrected claim.